I know many are looking for a doctor who can help with MTHFR mutations.
They are hard to find because very few doctors know and understand MTHFR mutations.
Then add on the fact that many doctors do not take MTHFR mutations seriously.
I do. You do.
MTHFR mutations can be serious and life-threatening. They can also be asymptomatic and not currently presenting problems. Important words here: “not currently” meaning that at any point they can start causing problems.
Given the complexity of MTHFR mutations, it will take a lifetime to thoroughly understand the nuances and optimum approach to each MTHFR mutation.
From my experience with MTHFR, I have learned the all important fact that we cannot blame all symptoms and problems on your MTHFR mutations. I wish it was as easy as that.
MTHFR mutations are ONE issue that is present in your life but it is not the only issue.
This is where one-on-one consultations with me become so valuable.
I combine the knowledge of MTHFR mutations along with the knowledge of other mutations (COMT, CBS, MTR, SUOX to name a few). Then combine this with nutritional biochemistry, environmental medicine (experts in detoxification and determining exposures) and the ability to understand where to start in all the myriad of symptoms.
For a limited time, I am available for one-on-one consultations.
If you’d like to receive assistance from me, I am here. Simply obtain how many minutes you’d like to schedule with me and then my team will call you to schedule the consult.
NOTE: Those wanting to consult with Dr Lynch must be truly dedicated to improving their health or their loved one’s health. If you are not committed to following through with lifestyle and dietary changes which are known by Dr Lynch to improve your health, then working with him is not recommended.
Do I treat, prescribe or diagnose people with MTHFR?
What I do in my consultations is provide you guidance, useful information, product suggestions, lifestyle suggestions and answer any questions you have. I also listen to you provide a thorough history and background. The more you share, the more I am able to dig deep and provide you with some great information.
I cannot, and will not, diagnose, treat or prescribe.
I do not have a clinic available and I do not want one as it limits my ability to help the millions who have MTHFR.
Consultations are $300 per hour and prorated by the time used. They are absolutely guaranteed or my support team will refund you in full. I want you to trust you are obtaining absolutely useful information in a way that you can apply it.
To schedule a consult with me:
- Visit the Consult with Dr Ben page at Seeking Health and select the amount of time you need. I also offer second opinions on your lab tests, if needed.
- Within 24 hours, you will receive a phone call from my team. They will schedule your consult with you over the phone.
- If you want to schedule and RSVP your consult over the phone, please call 800-547-9812. We can handle payment and scheduling for you efficiently.
During our consult, please be in a quiet area, take notes and make sure to provide me all pertinent information. I’ve heard it all so nothing shocks me. I also respect everyone’s unique situation and I hold no judgement. My goal is your health. Period.
Please comment below about any questions you have about the Consultations.
Questions you need you to answer prior to our Consult
- What would you like to achieve by the end of our consult? What is your goal?
- Are you willing to make significant lifestyle and dietary changes – such as eliminating wheat or dairy from your diet? I will ask you to do this.
- How committed are you in improving? Obtaining and maintaining health takes work and dedication.
- What are all symptoms you currently are experiencing? List in order of irritation and severity for you.
- How long has each symptom been present?
- What are your current diagnoses? How long have you been diagnosed with each one?
- What do you typically eat for breakfast, lunch, dinner and snacks.
- Any food or drink cravings? List them.
- What tends to make you feel better?
- What tends to make you feel worse?
- Gas, bloating, indigestion or belching? If yes, describe when and frequency.
- Describe the frequency and appearance of your bowel movements.
- Do you have difficulty waking up?
- Do you get dizzy on standing?
- Do you have access to a sauna?
- What is your blood pressure on average?
- Last use of antibiotics? What for? Probiotics taken afterwards?
- History of being prescribed and taken oral Flagyl, Tetracycline, Antacids, Antifungals, Steroids?
- List all medications you are taking – including over-the-counter.
- List all supplements you are taking and what time of day you are taking them.
- What do you do for a living?
- What hobbies do you do frequently?
- What are the significant stressors in your life? How you dealing with them?
- What are your outlets to reduce stress and increase relaxation/amusement?
- Tell me about your sleep. How much do you get? Difficulty with it in any way? Describe.
- Do you smoke?
- How much alcohol do you drink on average? Why do you drink it? Social? To relax? Like the taste?
- How many cups of coffee or caffeinated tea you drink in a day? Energy drinks?
- Describe your menses in detail.
- What would you like to accomplish in one month in terms of health goals?
- 3 months health goal?
- Any recent lab work? If so, what were the key findings? (If extensive, obtain the Lab Results and Records Review add-on for $150)
- Are you happy with your current doctor(s)? Why or why not?
- What is your current height and weight?
- When you drink water, does it tend to go through you quickly or stay in you for a while?
- How many times do you wake up to urinate?
- What over the counter medications are you currently taking? How often? Why?
In health,
Dr Ben
I am ecstatic to discover your website! Thank you for taking on this incredibly important health issue. I am a poor methylator. Two years ago Iab work showed that I am homozygoud for the A1298C gene mutation but NOT the C677T mutation. I do not see this scenario referenced yet on your web-site. As an RN and a Certified Nutritionist, I have done enormous amounts of research on this topic, and found little to no information to help me. I have numerous health concerns (including chronic fatigue) and am convinced that this is the core root of the problem. I react poorly to methyl donors as I have attempted to take DMG (everything in me aches when I take this), methylcobalamine SL (same reaction as DMG), and even some problems taking P5P (although I am able to take 25 mg now without such a severe response.). I have been told that taking supplements should not cause such pain/issues. I know I have a serious problem… but am at a loss for what to do about it. The physician uncovered the methylation problem treated me (DMG and then methylcobabamine) as he does all of his patients, and when listened to me explain my experience with each one, he told me to stop taking them, but didn’t have any other suggestions for me. (This is from a well respected Holistic physician’s group!) I would sincerely appreciate any and all information that you can direct to with!
Elizabeth -
I hear you loudly. The A1298C mutation is quite common – even more so than the C677T from what I’ve read.
A1298C is more complicated to approach as the biochemical pathways are…well…complicated.
Have you tried sauna? Epsom salt baths? Coffee enemas?
I will get a post on this soon enough – and videos – and podcasts
Dr Ben
Thank you for your prompt response to my inquiry. As I re-read my inquisition, I am mortified to see my grammatical errors… I apologize for those! (Apparently the anticipation of some long awaited ‘help’ temporarily clouded my writing skills!!!) I am more than eager to see/hear/read what you have to say about the A1298C methylation issues! I have been experimenting with L-5 MTHF (Designs for Health)… and sprinkling approximately 1/4 of a capsule on some food. This is enough to cause my hands to feel like they have arthritis! I should tell you that I am (perhaps due to this A1298C issue) extremely sensitive to most anything I take. For example, I have taken Energetix homeopathic detox products before and I only need a few drops (sometimes 2 will do it!) to feel/see a big reaction!!! I have read some of Dr. Amy Yasko’s books/research and I know that from the Autism standpoint, methylation issues can be provoked with tiny amounts of supplementation and cause all kinds of symptoms in Autistic children! Some call Chronic Fatigue Syndrome the adult version of Autism as it is biochemically similar issues! (BTW… I have a son that is on the high functioning Asperger’s Syndrome spectrum. What a coincidence, she said sarcastically!) Also for the record, IF I do an epsom salt bath, I can only soak for 10 minutes or so before I start feeling poorly — AND there will be a black residue at the bottom of the tub! If I sit in a far-infared sauna…. it takes me 10-15 minutes to start sweating (did I mention I’m generally cold — yes– subclinical hypo-thyroid issues!). 20 minutes will drain me for the day! I have never tried coffee enemas but I have read great things about them in Dr. Sherry Rogers books though!
When you say “soon” I hope you really mean it because I cannot wait to get some real answers to this issue. I do realize that I will most likely need to consult with you — for my sake as well as that of my two children! (My mother passed away from battling Metastatic Cancer of the Cervix 21 years ago…. and I am also convinced that this was the core of her problem!!!!! I don’t want any of us to have to repeat that scenario or anything like it!!!)
THANK YOU – Thank You – thank you for starting this website!!!
Elizabeth,
I have the same problem with methal donors and don’t know what to do either. Suggestions?
Jill –
You need to order a Methylation Profile test. This test looks at how one is methylating – or not methylating – and then provides an appropriate action plan based on the lab results.
A combination of MTHFR genetic testing along with a Methylation Profile Test is a good idea.
I am working on laboratories now to give MTHFR.net very low rates on lab testing. I currently have an agreement in place for the Methylation Profile. I am still working on the MTHFR genetic testing.
Best
Dr Ben
Please tell me again as I can not find my notes — which methylization test should I take. Also wondering, my daughter who is just six has been shown to have low B12 levels and some prfound tingling in her limbs. Could this be due to MTHFR and should I have her tested too? I have MTHFR c677T
Jill –
I highly recommend you get your daughter on some HomocysteX right away. She can swallow the capsules as they are quite small. Her B12 status needs to be increased and she may also have elevated homocysteine.
Try 1 capsule a day of HomocysteX for your daughter. If she appears in happy spirits, this is a good amount. If she begins to get irritable and grouchy, then skip a day. Try 1 capsule every other day. If she still seems grouchy at this point, reduce to 1/2 capsule every other day.
I would definitely test your daughter for MTHFR.
I am researching lab testing currently as I’ve been happy with the Methylation Profile but am not entirely happy with the ION Panel.
I have since discovered a better lab for those with MTHFR mutations and it is called the Cardio ION Profile by Metametrix. It is very comprehensive. The methylation aspect of the Cardio Ion is not as good as the Methylation Profile by Doctor’s Data but it provides a ton of other useful information that is badly needed – especially for those wanting to obtain a full term pregnancy, reduce cardiovascular risk and optimize their health.
I will be offering the Cardio ION Profile starting this week at HealthEGoods.com. Once it is listed, you will find it in the Lab Tests category or the Metametrix category (under Brands).
Cardio ION Profile is going to run about $925 and insurance won’t cover it. I want to state that it is worthy to order initially as it may discover some critical excesses and deficiencies.
I do not profit on these lab tests at all. I offer them purely as a service.
In health,
Dr Ben
We just got my two daugthers tested. the doc just ran a gentetic test through labcore. Both girls do not have my C667T, they have A1298C only one copy each. Both have normal homocysteine. My husband has had high blood pressure from his twenties and gets horrific migraines. I bet he gave them the copies. With this defect, her more natural doctor gave her Prothera Vitatabs and Douglas Labs Bcomplex with metafolin and intrinsic factor.
B Complex:
http://www.douglaslabs.com/pdf/pds/200765.pdf
Prothera:
Perfect for kids, or adults.
New, improved formula now contains Metafolin®**
L-5-MTHF.
These chewable multi-vitamin and mineral wafers are formulated with the finicky palates of children in mind. Kids who taste-tested this product gave their unanimous approval. Adults who have a hard time swallowing regular pills liked them equally well. Two tablets daily provides three times the RDA levels of vitamin C and E antioxidants, and twice the RDA for most B-vitamins. Added minerals in easy-to-absorb forms round out the formula. VitaTab® Chewable contains no artificial colors, flavors, or sweetening agents. Only all-natural flavors and sweeteners are used. Samples for taste evaluation provided on request.
Suggested Use: Children age 4 and over: Chew 2 tablets per day with meals. Adults: Chew 2 tablets, once or twice daily with meals.
VCW 60 chewable tablets
Supplement Facts
Serving Size 2 Tablets
Amount Per 2 Tablets % Daily Value
Calories 10
Total Carbohydrates 3 g 1% †
Sugars 3 g *
Vitamin A (56% (2,500 I.U.) as natural carotenes (alpha, beta, beta-cryptoxanthin, zeaxanthin, and lutein) from D. salina and 44% (2,000 IU) as vitamin A palmitate) 4,500 I.U. 90%
Vitamin C (as L-ascorbic acid) 180 mg 300%
Vitamin D3 (as cholecalciferol) 1,000 I.U. 250%
Vitamin E (as d-alpha tocopheryl succinate plus mixed tocopherols d-beta, d-delta, d-gamma) from soy 90 I.U. 300%
Vitamin K1 (as phytonadione) 80 mcg 100%
Thiamine (as thiamine mononitrate) 3 mg 200%
Riboflavin 3.4 mg 200%
Niacin (as niacinamide) 20 mg 100%
Vitamin B6 (as pyridoxine hydrochloride) 4 mg 200%
Folate (as Metafolin®** L-5-methyltetrahydrofolate) 400 mcg 100%
Vitamin B12 (50% as methylcobalamin and 50% as 5-adenosylcobalamin) 12 mcg 200%
Biotin USP 300 mcg 100%
Pantothenic Acid (as d-calcium pantothenate) 20 mg 200%
Calcium (as calcium citrate) 100 mg 10%
Iron (as carbonyl iron) 4 mg 22%
Iodine (from potassium iodide and kelp) 150 mcg 100%
Magnesium (as magnesium citrate-ascorbate complex 100 mg 25%
Zinc (as zinc glycinate chelate***) 5 mg 33%
Selenium (as selenium amino acid complex) 70 mcg 100%
Copper (as copper glycinate chelate***) 0.5 mg 25%
Manganese (as manganese glycinate chelate***) 2 mg 100%
Chromium (as chromium nicotinate glycinate chelate***) 120 mcg 100%
Molybdenum (as molybdenum glycinate chelate***) 75 mcg 100%
Boron (as boron aspartate-citrate) 1 mg *
Vanadium (as bisglycinato oxovanadium) 50 mcg *
Choline (as choline bitartrate) 5 mg *
† Percent Daily Values are based on a 2,000 calorie diet.
* Daily value not established
Other Ingredients: Fructose, dextrates, vegetable stearine, silicon dioxide, natural cherry flavor, natural orange flavor, maltodextrin, magnesium stearate, and licorice extract.
**Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany
***Albion® Laboratories
Is this good? He also gave her fish oil, Cal/mag/D…
Jill –
That is a pretty good formula yes. Cal/Mag/D and fish oil are also great recommendations. If she is not yet on a probiotic, needs to be.
Need to find out which mutation your husband has…
Helli Dr. Ben,
I am 30 yrs old & my husband is 31. We have been trying to conceive for 11 yrs. I have pcos & c6772 hetero. I have had 3 miscarriages & lost 4 babies. The only thing my dr. said totry is folgard, lovonex and prednisone & metformin. I just cant go thru another loss. Any suggestions? Thank you!
Wendy-
I have heard of this same scenario recently. There are many factors for miscarriage and being heterozygous C677T is minor – yet when combined with other things – may not be minor. Need to test your husband for MTHFR mutations as well. He may be passing them onto baby.
Definitely need to resolve the PCOS as that is going to cause your progesterone levels to be inadequate.
Prednisone: what for??
You have to be fully willing to change your diet and lifestyle if you want PCOS to resolve naturally – and it can. I’ve helped women out of it before and 100′s of other doctors have as well.
You have to be committed though.
I would have your doctors check your:
- thyroid
- cardiolipin
- antiphospholipid syndrome
- hashimoto’s thyroiditis
- celiac disease
- CRPhs
- serum ferritiin
- comprehensive female hormone panel
- test husband for MTHFR mutations
In the meantime, do not get pregnant until you isolate the cause of the miscarriages. You can if you have a good doctor.
Get the testing done above and see what they find. If nothing, I recommend scheduling a consult with me.
Love to see you have a little one in your family.
Glad to see this website. First learned of MTHFR because of my son having high functioning autism. The more I learned, the more I’m convinced that my husband’s family has this deletion. Other maladies in his family: schizophrenia, bipolar plus my husband developed a deep vein thrombosis with pulmonary embolisms last summer. The doctors could not give us a reason since none of the usual causes were there. He’s been on Coumadin since the event. I ask his Dr about Nattokinase, but she didn’t really know anything about the supplement. Finally a substitute doctor (my husband’s Dr. was on maternity leave) ran homocysteine levels and they were elevated. At this point, a lot of light bulbs were going off because he was starting to talk about things that I’ve learned at Autism conference. Did a little research of my own when we got home and found http://www.ncbi.nlm.nih.gov/pubmed/15670035 “Homocysteine, MTHFR and risk of venous thrombosis: a meta-analysis of published epidemiological studies.” So I immediately started giving my husband the same supplements that were recommended to my son for HFA; methyl B12; DMG w/methyl B12 & folinic acid, and L-MethylFolate. My husband has a return appointment coming up and I am definitely going to insist that they test for MTHFR. Hopefully, the supplements have improved his levels enough to keep him off of their pharmaceuticals. Not crazy about him being on coumadin.
Dear Dr Ben,
I would like to do a consultation with you but I want to make sure I have enough information for you to help me. My son is diagnosed pdd-nos he is 6 years old and is heterozygous c677t and a1298C. His homocysteine level is ok. He is extremely distracted and seems much more ADD than anything. He has had chelation in the past for high urinary porphyrins. (Which I will be testing again on Tuesday) He was gluten free casein free for 2.5 years then we did NAET and introduced the foods again and didn’t notice any change whatsoever. He has been getting strep infections lately and is a poor sleeper – either having nightmares or wakes at 4:00 for the day. He is extrememly inconsistent with his behaviors – doing well some days (happy and more focused and some days sooo inattentive and cranky). I have a metametrix 3400 NY triad profile and wonder what other info/labs would be helpful. I am wondering what supplements you recommend for him and how we can help him. It’s been a long 6 years and we have tried so many different biomedical therapies/supplements…they all seem to blend. He is currently on augmentin for strep and we give him probiotics but that is the only supplement we are currently doing right now. (oh I did give him zinc this AM because he is chewing on his sleeves, jacket, blanket – anything he can chew on)
Any suggestions are greatly appreciated.
Thank you,
Ginette
Ginette –
I am sorry to hear of your son’s symptoms.
I see some things which make me suspect heavy metal toxicity – the high porphyrin test. Has he been chelated for heavy metals?
The MTHFR mutation that he has, compound heterozygous, definitely throws off his neurotransmitters. I suspect he has other mutations which are contributing to his symptoms – beyond MTHFR. I soon will have a lab test which will help identify these so we can work with them and around them.
NAET I do not believe in. Don’t rely on that to eliminate allergies or food intolerances. These foods have a big impact on neurotransmitters and must be eliminated long term.
No wheat. Ideally no gluten.
No dairy.
Start keeping a journal of his days – and what is eaten – and what is done. See if you can find patterns in his behavior. Food is a huge component here and so is the environment.
There is WAY more to do for a compound heterozygous that goes beyond homocysteine levels being optimized – yet docs don’t realize that.
Once I get the test available, order the test and once you receive the results, a consult should be scheduled.
For now, keep him off all gluten and casein – completely. Keep him fed throughout the day – smaller meals but each one having some form of protein.
I’d also recommend you get him on ProBiota 12 Powder – 1/4 teaspoon after dinner and 2 hours after you give him Augmentin. If you give it earlier than that, the Augmentin can kill the probiotic. He also needs to be taking Saccharomyces Boulardii – 2 capsules in the evening. These both are CRITICAL for his digestive health.
I also recommend 7 drops of Liquid Vitamin D360 ONCE A WEEK – not daily. This provides 2,000 IU per day dosing – just done once a week to make it easier on you and him.
Consider giving him 1 chewable tablet of Optimal Multivitamin with breakfast and 1/2 tablet with his lunch. This provides essential minerals in their well-tolerated and absorbed forms along with effective forms of B vitamins – including methylfolate and methylcobalamin.
I would also consider giving him 1/2 tablet of Active B12 with Methylfolate. This is a sublingual form of methylcobalamin and methylfolate. A 1/2 tablet is recommended in the beginning as we want to ensure he responds well to lower amounts first.
Consider giving him 1 capsule of Magnesium Plus before bed along with 1 capsule of Ashwagandha. These may help reduce his nightmares.
There are more lifestyle and dietary changes along with specific supplement suggestions but are impossible to recommend without a consult and additional labs.
Dr Ben,
Thank you for your quick response and I will definitely look into those supplements for Tyler.
Yes, we have done IV chelation with Tyler for about 9 months. This was about 2 years ago – a lot of lead, nickel, and uranium was drawn out. Do you think this is something which will have to be done throughout his life since he seems to continue to accumulate the heavy metals?
Tyler was never vaccinated so the contact with heavy metals must be environmental.
Also – we live in NY – so our physician must order any labs – is that correct?
Thanks,
Ginette
Ginette –
Yes your doctor in NY must order the labs directly.
Those with MTHFR mutations do accumulate metals and chemicals more so than others. Detoxification is a life-long process – not a one-time shot.
Keep in mind that Tyler’s heavy metal load could have come from you while in utero. You should be tested as well.
Dr Ben,
So great to see this website. I first heard of MTHFR when my son who was born premature at 26 wks and also suffered an in utero stroke. He participated in a stroke study and it was found he had C667T. I was told it shouldn’t matter for him but if he was a female, that down the road estrogen could have affects. My son has CP, but otherwise seems healthy. 2 yrs prior to his birth, I suffered a PE with birth control pills being the only found contributing factor. I was told, don’t take hormones again. In 2008 I suffered another PE early in pregnancy before Lovenox treatment was started; so clearly there is a hormone connection. I requested to be tested for MTHFR and I too have C667T, and normal homocysteine. In 2010, I suffered a third PE, no known trigger, Coumadin for life sentence. In the last 3 yrs I have had other thing like irritable bowel that by my own trials find may be connected to dairy, strange mild headaches, back pain and stiffness in the morning. These latter things, I assume are nutritionally caused, so very interested to hear MTHFR may have a connection. Any suggestions for my son or myself are very welcome.
Carolyn –
It has NOTHING to do with sex and MTHFR. Given that your son has MTHFR C667 – he needs to be on the proper protocol that is right for him – and you need to be on one that is right for you.
Normal homocysteine is not the only lab marker to determine blood clotting. Research shows that low methylfolate levels along with low methionine are indicative of increased pulmonary thromboses.
What is ‘CP’ – sorry – too many abbrevs to remember in medicine.
Too much estrogen is linked to clotting- yes. But in your son’s case – I doubt estrogen is the reason. MTHFR 677 causes strokes..
IBS is definitely related to diet and digestive flora – and also a healthy gut lining. Low methylators – such as those with MTHFR mutations – are more prone to digestive disorders.
You both need to get on a MTHFR protocol if you have not yet started one. A consult is needed to get you on the right track.
Thank You Dr Ben,
I will have to get my questions and answers together and schedule a consult.
CP = cerebral palsy – due to stroke and prematurity. Of course I want to give him the best odds at brain health. I also think there is a connection between his gut and his dystonia as in when his digestion is sped up his dystonia is lessened. I think?
Carolyn -
Gut/Brain connection is very real. Foods create neurotransmitters so there is no question there is a link.
Please avoid all wheat and ideally gluten – and dairy products. It is a difficult transition at first but very worth it in the end – for all of you – not just him.
Right now, consider getting your son on 1 capsule of Optimal Brain daily.
Look forward to working with you and your son.
Hi Dr. Ben,
My husband found your website while researching MTHFR. We’d love your advice on our situation.
We started trying to get pregnant in 2009. Had no issues getting pregnant the first time, and everything was great until the 12 week checkup. The doctor couldn’t find a heart beat with a doppler, so he performed an ultrasound and the baby had passed around 9.5 weeks. He chalked it up to bad luck, everyone has at least one miscarriage and told us to try again. My next pregnancy was a chemical. My OB ran some blood work, discovered that I had homo c677t and put me on extra folic acid, baby asp. and a prenatal with extra folic. I asked for Lovenox; she said too extreme, not needed.
The next pregnancy, I carried to 10 weeks, before we had the same scenario; no hearbeat on the ultrasound. Less than a month later, I got pregnant again with twins. This time, my doctor put me on lovenox. I carried the first twin to 8 weeks, then it passed. The second one to 13 weeks, before discovering no heartbeat again. We heard the heart beat the day before we found out we lost the baby.
I started seeing an RE who advised that I was not taking the lovenox shot early enough. He placed me on the shot four days after ovulation. I was on NEEVO prenatals, folgard, folbic, baby asp. and the shot. NOTHING. I went through about 8 rounds of trying to get pregnant with this combination and cannot even get pregnant now. The doctor did a lap, removed a small amount of endo and said I should be able to get pregnant. Still nothing.
Any advice on the miscarriages and the treatment prescribed or why I’m not having any luck getting pregnant now? We used fertility drugs with the RE and inseminations.
Thanks for your help,
Jessica –
Sorry to hear of your struggles.
There are many reasons for infertility and miscarriage.
Taking fertility drugs are not the answer in my mind. There is some imbalance in your body that must be restored and drugs are not repairing that imbalance – they are merely putting a bandaide on it – if that.
You cannot force fertility – the body is truly inherently wise at what it can handle and what it cannot. Combine this with the MTHFR C677T homozygous mutation and it makes it more complicated.
With the right laboratory tests, diet, lifestyle and nutrients, I firmly believe many can become fertile and carry a baby to term – and deliver a beautiful little one that is healthy.
Given that you’ve miscarried early so many times, I question your progesterone levels. I don’t see any doc working in that area with you yet.
Lovenox, baby aspirin, methylfolate (about 4 mg), methylcobalamin (about 5 mg) and a comprehensive multivitamin, CoQ10, probiotic, vitamin D3 and cal/mag are needed in my book for a healthy MTHFR C677T homozygous woman – and – perhaps some added progesterone as well. That said – diet is critical and so is evaluating thyroid, adrenals, sleep, your environment, stress, etc.
I’d like you to order some bloodwork and urinalysis and then schedule a consult.
Ask your doctor to test:
- Comprehensive female hormone panel
- Thyroid panel: TSH, T3, T4, rT3, anti-TPO, anti-TG
- CBC with chem panel
I’d also like you to avoid gluten (at least wheat) and dairy products. Completely.
I have nutrients specific for optimizing pregnancy for those with MTHFR mutations but a consult is needed first I believe – and ideally some testing.
We can greatly increase your odds of having a child – will take some sleuthing – but the outcome is a lifelong reward
Hello,
I am so glad I found this website! I have 2 copies of the A1298C gene mutation. I have recently recovered from a long illness with lyme disease. I do still have fatigue among a few other problems. What do you recommend for this gene mutation? I do not find any information on it.
I also need to have my oldest son tested. He is 7 years old and has some ADHD symptoms as well as an odd stutter at the end of his words. I would love to somehow have him tested for this gene.
Thanks for all the information you have posted!
Kylie
Kylie –
Please do get your son tested for MTHFR.
There are many things you can do for A1298C and Lyme. I am working on preparing more information for people and will publish it. Issue is I’ve been so busy with consults – my time is limited.
I am going to have to further reduce how many consults I allow in a week.
For now, really focus on a healthy digestive system. The key is to limit ammonia production internally and process it properly with nutrients, diet and lifestyle.
Hi Dr Ben,
I wrote to you a few weeks ago about my son, who is a compound heterozygous – I just found out I have the exact same mutation as my son. I took Deplin today – 15 mg and was so exhausted I almost immediately fell asleep and felt tired all day. The Dr prescribed it for my son but I wanted to see how I felt on it before I have it to him. Do you have any insight as to why it would make me feel so tired? Now I’m afraid to start my son on it.
Thanks,
Ginette
I was so happy to see this website and to see that research is being done on MTHFR. I feel like I have been dismissed by so many doctors that my homozygotic MTHFR gene mutation has nothing to do with my 6 recurrent pregnancy losses.
I have taken baby aspirin and folic acid to no avail. I am hoping to find a doctor that will be more aggressive in treating me and hopefully having a successful pregnancy.
I also have mthfr…..i have had 8 pregnancies 1 i lost at 5months i ended up with hellp syndrome…..i almost died and lost my son after 12 days….since then ive been on asprin folic acid progestrone and lovenox and still miscarry between 6 to 8 weeks so this last time i was only on folic acid baby asprin….my drs said taking lovenox and progestrone doesnt mean i will go full term:(……….i dont know wat to do cause my first one i was on nothing and made it that far…….im just tired losing all my babies!!!! and i feel as they dont care all i get is there is hope try again……
Patty –
Sorry to hear about your lack of help and miscarriages.
Which MTHFR mutations you have?
I would like to make an appointment for a consultation with you but want to know if I can have an appointment for not just one person (myself, my husband, my children) but instead a comprehensive appointment for my family?
We are a complex family of mthfr and other health issues. We have 3 heterozygous 677, 1 compound heterozygous 1298 & 677 and 1 homozygous 677. I could not afford 5 separate appointments that I’m sure I will need followups for.
I understand that each person is unique and will have their own set of rules to follow but I am hoping that with a deeper understand of what to supplement and what to watch for. Do you do comprehensive family appointments where you can give a general guideline for how to treat everyone in your household individually?
Kim
Hi Kim –
I just did this yesterday for a family. It took 1 hr to go over 4 people.
There was an initial consult which led up to the family consult – the first 30 minute consult was for a very difficult child – who by the way is doing much better now
Look forward to talking with you
Dr.Ben,
I’m about to schedule an hr consult. Just got results from you yesterday. C677T homo. Should I order methylation panel first?
Also, in terms of other tests done before consult- I have very high Dopamine, Norep,Gaba and body isn’t breaking down these or Serotonin so I have a reaction to any supplement that effects nuerotransmitters .(feel like I’m going crazy). I’ve heard you talk about people’s reaction to methyls due to other mutations. If I already know I have elevated nuerotransmitters and I don’t want to take anything that will make them higher, but instead something that will help the enzyme break them down…what tests should I do ? what can I take to help this process?
I’m not sleeping or eating much right now, my body is actually vibrating. My ND says she doesn’t know what’s exactly wrong with me and for me not to take anything , so I’ve been stuck and not doing well at all. She says it’s a hormone imbalance combined with enzyme issue, so everytime a hormone rises or I take anything…it pushes nueros higher. We need to figure out why they’re not breaking down.
Besides the questions you listed above, what info can I prepare before consult that will help you? I have wellness panel, thyroid panel, neg for leaky gut & parasites, slightly elevated mercury & lead- took 4 out of 6 fillings out last month.hormone panel showed very high testosterone & dhea..pregesterone high due to cream use which I stopped using. took 500mcg folate w/NAC for a week, did ok. Did 1mg & added B12 & had horrible almost mania type reaction.
In the meantime, is there any supplement that I can take to either bring down my excitotorys or help me calm/sleep?….I’ve had reaction to Gaba,Theanine,Insoitol,taurine,tryptophan,Lithium Orotate,phenibut,melatonin. .
Thanks,Kimberly
Kimberly –
Given your history, a methylation panel may be a good idea prior to our discussion; however, the main issue appears to be relating to neurotransmitters – which is linked – yes – but we may be able to make some headway right away. You may have a COMT and MAO A mutation.
I have ways to help calm them down. I am currently researching other methods as well – actually just this morning I have been researching GABA and Glutamate imbalances, why and how to address them.
This morning I hadalready ordered a consult for Monday, so I guess we can discuss then on what future tests or steps to take. Meanwhile, I will steer clear of Methyls.I’m taking Niacin and B6 with Magnesium., Epsom salt baths and activated Charcoal at night.
Took 250mcg of Folate today to test and sure enough a few hours later I felt as though I was drugged; joints in hands ached, lethargic, dizzy, headache.