Folate and MTHFR: Are They Affecting Your Pregnancy?

Shop-ImageWritten by Dr. Carolyn Ledowsky

For many, the diagnosis of a MTHFR mutation comes after the heartbreaking process of trying unsuccessfully to fall pregnant or maintain a healthy pregnancy.

As we know, one of the primary functions of folate and the MTHFR gene is to govern the production of healthy DNA, which is in peak demand during the rapid growth of a foetus during pregnancy.

Ensuring folate levels and the MTHFR gene are functioning optimally are vital steps in any pre-conception plan, and are necessary investigations for every couple (both male and female) that are wanting to or are having trouble falling pregnant.

The founder of MTHFR Support Australia (, Carolyn Ledowsky ND,  is running a webinar on this important topic to provide education, support and information for those who are positive for the MTHFR gene, and want to understand how this is affecting their fertility and the steps for a healthy pregnancy.

Who Will Benefit from this Webinar?

The webinar will provide information on MTHFR and methylation for couples who:

  • Know their MTHFR status and are wondering how it may impact their fertility and pregnancy.
  • Are wishing to begin pre-conception care.
  • Are currently attempting to or are unable to fall pregnant.
  • Are currently or have suffered from pregnancy related issues such as recurrent miscarriages, thrombophilia or preeclampsia.
  • Are currently undertaking IVF or have been diagnosed with unexplained infertility.
  • Have had a previous child/ren diagnosed with MTHFR-related conditions such as ADD/ ADHD, Autism, Down’s Syndrome, learning or behavioural issues, cleft lip/ palate, Congenital Heart Defects or Neural Tube Defects, and wish to know how to prevent these in future pregnancies.

You Will Learn in the Webinar:

  1. What happens in each of the three trimesters, and how that is related to folate and MTHFR.
  2. The factors that affect male and female fertility.
  3. The correct investigations and pathology testing needed to reveal factors affecting your fertility.
  4. How folate and MTFHR specifically impact on pregnancy and the growth of the foetus.
  5. How dysfunctional MTHFR and methylation then go on to affect:
    a) Preconception

b) Pregnancy

c) Foetal development

  1.  What specific steps to take before and during your pregnancy if you are either homozygous or heterozygous for the MTHFR gene mutation
  2. The optimal diet and lifestyle for those with the MTHFR wanting to fall pregnant
  3. Specific nutrients and doses for supporting your healthy pregnancy with MTHFR.

We hope you’ll join us for a highly informative and valuable webinar, as it is information that can impact the health of your and your family to come.

The Details:

The webinar has limited spaces, so please click the link below for more information and to secure your seat:

It will be held on the 24th of June, 8pm Australian Eastern Standard Time.

All who attend the webinar will receive an information pack of handouts and resources for your pregnancy journey, full presentation slides and unlimited access to the webinar for 60 days after the live event.

MTHFR Support Australia founder and naturopath Carolyn Ledowsky will also be able to answer any of your questions surrounding MTHFR, pregnancy and what it means for you.

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5 Responses to “Folate and MTHFR: Are They Affecting Your Pregnancy?”

  1. Claudia June 23, 2014 at 5:52 pm # Reply

    Is there any way to purchase the slides and download the webinar without being online in real time? I am on the eastern time zone US and really need to see this but can’t participate due to the time zone difference. I have two copies of mthfr 677ct, have miscarried three times in the last two years and desperate for this information. Thank you!

  2. Lina June 29, 2014 at 6:21 pm # Reply

    I´m in the exact same situation as Claudia who wrote the previous comment. I haven’t miscarried but have gone through 5 AIs and 2 IVFs to find out that I’m a poor responder.
    Got tested only a few weeks ago for MTHFR as part of a treatment to hopefully regain naturally my ovarian response, and the result shows two copies of 677ct.
    Is that the reason my egg quality is low? can it be reversed? I’m taking Thorne’s Methylguard. Or should I go directly to find an egg donor because of this genetic condition I just discovered.


  3. Cheryl July 14, 2014 at 8:58 pm # Reply

    Hi – I am thinking this information is too important not to reach a wider audience. Is there a way to get the information if you did not attend the webinar?
    Thank you.

  4. Denise George July 16, 2014 at 3:46 am # Reply

    I followed the link above and found this information:
    MTHFR Support Australia &
    Northbridge Nutrition & Natural Health
    333 Sailors Bay Road,
    Northbridge NSW 2063
    Tel: 1300 692 260

    I also saw it cost around $30 and if you secured a seat there was access to a recording for 60 days. Hopefully, by ssending an email you will get an answer

    I wish you the best of luck in your quest. I went through 1 ectopic pregnancy and 3 miscarriages… i was blessed wirh a child before my miscarriages. Im currently post menopausal at 43. I wish this information was available then. I wish you the best and hope you find some answers and conceive and deliver many bright, healthy children!

  5. Tanya November 7, 2014 at 11:02 pm # Reply

    Hi, Can anyone tell me if overmethylation is dangerous during pregnancy? I had six miscarriages before having my amazing boy. I would like to give him a sibling and feel I need to increase the amount of methylfolate I was taking. My amazing little man was born with a sacral dimple (benign, but related to spina bifida) and tongue tie – he is fine, (better than fine, he is sensational – does not sleep well at all, but sensational!) but I think these are indicators of not enough methylfolate. My issue is, I have increased my intake of methylfolate while still taking b12 and other recommended suppliments and I am feeling the effects of overmethylation (along with being tired due to my little man not sleeping well). I am older in age, so I can not wait to start trying again, I am already on borrowed time due to my miscarriages. I know I have a comt, plus other genes not great for using folate and oestrogen… so I am asking if the overmethylation causes probs ? does it increase the chances of blood clotting or any other side effect that would be harmful if pregnant. Kind regards Tanya

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