Confused about reply to Rachael today on treatment plan for C677T Mutation

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This topic has 2 voices, contains 1 reply, and was last updated by  Dr Ben 93 days ago.

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February 15, 2012 at 9:39 pm #872

Pat

Dr. Ben,

I was excited to see you help Rachael with a “getting started plan” to treat her C677T Homozygous mustation. I was just wondering what the rationale is for going from Active B12 5000 to B12 with Methylfolate and then to Homocystex since they all have the exact same amount of Methylated B12 and Folate in them? I realize it may have something to do with the first 2 being sublingual(why not stick with just one of those?). I know that Homocystex has B6 added.
February 15, 2012 at 10:16 pm #873

Dr Ben

Pat -

I work up based on ingredients.

If they respond well to B12 – great
Move to adding methylfolate – respond well to that – great
Move to adding P5P -respond well to that – great –
Move to adding Betaine –

Step by step process.

One may feel good with B12, but better with methylfolate, and even better with B6 and even better with Betaine and B2.

However, cannot just start right away with all the ingredients – can backfire.

Everyone is different and in order to limit side effects due to poor response to a specific ingredient – and to ease into activating methylation – this is what I have seen work well for people.
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