heterozygous MTHFR A 1298C in pregnancy

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This topic has 2 voices, contains 2 replies, and was last updated by  hope 82 days ago.

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February 17, 2012 at 5:49 pm #921

hope

I’m interested if that mutation can cause problems in pregnancy and if is necessary to take baby aspirin as treatment. am on a treatment with folic acid 5 mg and pronatals! do you thinknis enough?
February 20, 2012 at 3:41 am #964

Dr Ben

Hello –

The heterozygous A1298C MTHFR mutation is less likely to cause an issue in pregnancy – however, if combined with other mutations or poor digsetive health, then it can make it worse.

Please read this article on prenatal supplementation.

I also do not think you need to be taking 5 mg of folic acid with a heterozygous A1298C MTHFR mutation. I think that can cause issues.
February 27, 2012 at 12:39 pm #1072

hope

Thank you for your answer! I have also the mutations of PAI 1 675 4G heterozygous and 844>G also heterozygous. These mutations can cause problems in pregnancy asociated with MTHFR A1298C heterozygous? Do I need a treatment in order to avoid a misscarige? I am five weeks pregnant now.
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