Why MTHFR is Becoming Recognized

For millenia, humans have walked the planet.

We’ve continued to evolve and develop as a species:

  • walking upright
  • less ‘fur’
  • learned farming and ranching
  • further understanding of how the world works
  • further understanding of how biochemistry works
  • transportation
  • communication
  • creating and developing new technologies
  • eliminating or seriously reducing common causes of death

In our on-going push for development, we’ve begun to get off track and in some ways – seriously.

  • Food is no longer food.
  • Water is no longer water.
  • Air is no longer air.
  • Soil is no longer soil.
  • Animals are no longer animals.
  • Bugs are super bugs.
  • Medicine suppresses – not heals.
  • Not everything naturally decomposes.
  • Electromagnetic radiation permeates us from all directions constantly.

What do all these have in common?
Toxicity and Xenobiotic Exposure.

When you add up the effects from the list, it is readily apparent how toxic and loaded our bodies are.

How does our body eliminate toxins, stress hormones, histamine and xenobiotics?
Methylation.

How do we support methylation?

  • Healthy, whole food prepared properly
  • Organic vegetables and fruit – really organic (not middle of the night diluted organic standards for big corporations)
  • Leading lives of healthy thoughts and interactions
  • Sleeping well
  • Eliminating and defecating twice or more daily
  • Exercising
  • Pure water
  • Avoidance of toxins, xenobiotics, stress, chemicals, artificial anything.

Are you supporting methylation?
Take a step back. Are you supporting methylation?

Are you trying to support methylation but finding it extremely difficult because you are:

  • Working 40+ hrs a week with only 2 weeks of vacation a year (if that)
  • Eating on the run
  • Stressed
  • Commute to work inhaling toxins and exhaust
  • Sit inside inhaling countless chemicals and solvents
  • Eating processed foods
  • Eating genetically modified foods – including wheat (altered to have more Gluten)
  • Cooking with a microwave
  • Drinking soda, juice, bottled water or unfiltered water
  • Eating, drinking, cooking or storing foods in plastic, teflon, non-stick, aluminum
  • Not exercising
  • Not sleeping well or not enough
  • Taking various medications
  • A parent dealing with your children
  • A child dealing with your aged parents
  • An individual caring for someone ill

Combine the factors which support methylation against the ones that antagonize it.
Do you find that you support methylation more than not? If so, you should be quite healthy.

Do you find that you antagonize methylation? If so, you should be quite ill or getting there.

Why has the MTHFR gene mutation become an issue worth understanding?
Methylation is severely lacking due to lifestyle, dietary and environmental exposures.

DIS-ease and dysfunction are present if the body cannot obtain, process and utilize the nutrients it needs to in order to support methylation.

If you add genetic polymorphisms to the already apparent lack of methylation, disease and dysfunction are going to be amplified.

This is why the MTHFR polymorphism is coming to a head.

MTHFR is at the CENTER of methylation – literally.

If a MTHFR defect exists, then methylation is slowed immensely.

A scientific paper on this matter identifies the methylation issue well:
The metabolism of methyl-consuming compounds generates reactive oxygen species and consumes labile methyl groups; therefore, a chronic increase in the levels of methyl-consuming compounds in the body can induce not only oxidative stress and subsequent tissue injury, but also methyl-group pool depletion and subsequent aberrant methylation status. In the past few decades, the intake amount of methyl-consuming compounds has substantially increased primarily due to pollution, food additives, niacin fortification and high meat consumption. Thus, increased methyl consumers might have a causal role in the development and prevalence of metabolic syndrome and its related diseases. Moreover, factors that decrease the elimination/metabolism of methyl-consuming compounds and other xenobiotics (for example, sweat gland inactivity and decreased liver function) or increase the generation of endogenous methyl-consuming compounds (for example, mental stress-induced increase in catecholamine release) may accelerate the progression of metabolic syndrome. Based on current nutrition knowledge and the available evidence from epidemiological, ecological, clinical and laboratory studies on metabolic syndrome and its related diseases, this review outlines the relationship between methyl supply-consumption imbalance and metabolic syndrome, and proposes a novel mechanism for the pathogenesis and prevalence of metabolic syndrome and its related diseases.[1]

 Take Home Points on Methylation:

  1. Address the things in your life that are depleting your ability to support methylation.
  2. Continually improve the activities in your life that are increasing your ability to methylate.
  3. Identify genetic defects which alter methylation and assist in the restoration or bypassing of these defects

Write your thoughts below by leaving a comment.

11 Responses to “Why MTHFR is Becoming Recognized”

  1. Danelle February 15, 2014 at 4:26 am #

    Is it harmful to start taking Methylfolate while pregnant? I just found out that I have 2 copies of the MTHFR C677T mutation and I am pregnant.

  2. Summer April 7, 2014 at 10:55 pm #

    Not sure if this is the right post to ask this question; I’ve heard the MTHFR mutation can cause clotting by interrupting blood thinning? Is that correct? If so does this explain why I have very heavy periods with lots of large clots? Will treating correct this?

  3. Carrie May 27, 2014 at 12:46 pm #

    I have 2 children one at the age of 20 – great pregnancy other than preeclampsia and then when I tried to conceive started the miscarriages 4 sweet angels, then it was discovered that I have double strand MTHFR… I was put on Prenatal Vitamins, Folbic, Daily aspirin, and Lovenox injections daily – I have a VERY HEALTHY little boy now who I call my little miracle.

    I have this I have been told that I am at risk for blood clots (found that out when I wanted to go on birth control). My question is NOW what do I need to worry about – I am 39 this October and I am overweight. Please help me learn what I can to prevent any other issues from this mutation. What other causes or issues can this mutation cause. I thought it was only a worry when I was pregnant but now I am not so sure.

    Thank you –
    Carrie

    • Dr Lynch May 28, 2014 at 4:05 am #

      Hi Carrie –

      It’s important to be proactive all throughout your life – and your child’s life as well as they have MTHFR as well.

      Pleased to hear about your healthy boy 😉

  4. Carrie December 28, 2014 at 1:10 pm #

    I have a question my daughter who will be 19 is a double strand carrier. My son who is now going to be 2 yr and 7 months soon has not been tested but is chronically ill. The doctors have sent is to an infectious disease doctor with everything checking out normal there. What issue or where can I find them in the internet could this double strand have onmy son if he is a carrier? Please ANY help is appreciated. He is sick every 2-3 weeks since he has been 6 months old – I just want him better. B

    Thank you in advance –
    Carrie

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