“MTHFRade” is the MTHFR Drink Formula. Have yours yet?

Having done 1000’s of consults for MTHFR and working with nearly triple that through email correspondence, I have seen a trend that must be made public knowledge.

I am seeing sometimes incredible improvement in energy, muscle health, decreased muscle pain, improved adrenals and decreased frequency of urination through a drink mix I’ve created for my clients.

Some MD made the Florida Gators a pretty famous drink. You may have heard of that corn syrup laden, food colored beverage called Gatorade.

I welcome you to try MTHFRade.

UPDATE: October 1, 2014

MTHFRade has worked wonders for many people so I made an all-in-one formula called Optimal Electrolyte.

Same ingredients as I recommended for years – but only better in taste and potency.

Easier to use now – just add one scoop – no buying 5 different things and mixing them together. With that said, it is also significantly less expensive than buying all 5 ingredients separately.

It comes in two flavors which taste absolutely incredible – kid approved (my kids). Berry and Orange.

What does Optimal Electrolyte contain?

As with any of my formulations, it provides solid amounts of well-researched ingredients which are needed to balance your electrolytes.

  • Magnesium
  • Potassium
  • Sodium
  • Creatine
  • D-Ribose
  • Niacin
  • Taurine

end of update – original article below – 

Dr Lynch’s MTHFRade consists of the following mixed in a 1 liter stainless steel water bottle:

  1. Filtered water
  2. Electrolyte Concentrate: add 6 to 9 capfuls per liter.
  3. Optimal Vitamin C Powder: add 1 to 2 scoops per liter.
  4. D-Ribose Powder: add 1 to 2 scoops per liter.
  5. Optimal Creatine: add 1 to 4 scoops per liter.

Benefits people are experiencing from MTHFRade:

  • Decreased urination (those who were urinating too frequently throughout the day/night)
  • Improved energy
  • Decreased ‘brain fog’
  • Significantly reduced symptoms of chronic fatigue and fibromyalgia
  • Increased hydration
  • Ability to absorb critical nutrients easily
  • Decreased dry mouth and dry skin
  • Decreased muscle cramps

How to drink MTHFRade?

  • Desk jockey? Mix in the morning and drink throughout the entire day. Keep this at your desk and take sips throughout the day. Do not drink all at once.
  • Exercising? Mix prior to your exercise routine and take with you. This helps prevent muscle cramps, increases energy and performance.
  • Sauna or Epsom Salt Baths? Mix prior to your epsom salt bath and take with you. Drink during your epsom salt bath – and afterwards to prevent electrolyte loss and improve the benefits of the epsom salt bath.

How does MTHFRade taste?
In my opinion, excellent. A bit sour, a bit salty, a bit sweet. My children even enjoy it. So far I’ve had no complaints.

Are there any artificial flavors, colors or preservatives in MTHFRade?
Need you ask that? Come on now. None. Absolutely none.

Are there are any potential side effects from MTHFRade?
Some may find increased gas initially. If this is the case, simply reduce the amounts of all the nutrients by half and then work up to what is comfortable for you.

Some may find their stools are a bit harder to pass if they add too much Electrolyte Concentrate. This makes sense. Find your balance. The recommended amounts are commonly well tolerated.

Some find they no longer crave the sugary drinks or energy drinks like they used to.

NOTE: Some may find themselves drinking more than one liter of this solution daily (I am guilty of this). Is this ok? Yes. Not a problem as long as your digestion and body welcome the nutrients.

I’m drinking it right now, in fact. How do you think I get through so many consults in a day plus all the emails? :)

Give MTHFRade a shot. Let me know how it has improved your symptoms after you’ve tried it for a week or so.

, ,

90 Responses to ““MTHFRade” is the MTHFR Drink Formula. Have yours yet?”

  1. Elizabeth January 22, 2012 at 12:49 am # Reply

    Hello Dr. Lynch…
    Can you verify for me that it is okay to take d-ribose if one has yeast issues/concerns?

    • Dr Ben January 23, 2012 at 6:50 am # Reply

      Elizabeth –

      D-Ribose is a sugar highly utilized by your muscles. What I recommend doing is drinking a little of it throughout the day – which is what you are doing in MTHFRade.

      Many take D-ribose all at once – a 5 gram scoop – you will be taking it in small amounts all day long.

      I highly recommend potent probiotics such as ProBiota 12 Powder, Saccharomyces Boulardii and also an antifungal blend such as Microbial Defense. These and a brief explanation of why/how to use them is found here in the Yeast and Candida Elimination area.

      • Elizabeth January 23, 2012 at 7:56 pm # Reply

        What is your take/opinion on alkaline water (naturally alkaline or machine made alkaline)? I can feel fairly lousy when drinking this, even just a glass or two a day! I don’t know if that is good for me, although theoretically, alkaline water is detoxifying. However… if my body, d/t complex methylation issues, cannot eliminate what the alkaline water might be ‘detoxing,’ then this is probably not wise. I am interested in your opinion. Thank you.

        • Dr Ben January 23, 2012 at 10:04 pm # Reply

          Elizabeth –

          That is interesting. I am not sure of this connection. I do not see a connection but it may exist.

          If you find out something that is credible, please do let me know.

          I own and use an Akai Water Ionizer and use it for my family. We feel great with it.

          • Elizabeth January 26, 2012 at 11:36 pm #

            I do not know if there is a connection or not. I seem to react to sooooo many supplements that I am becoming a big paranoid about things that may be exacerbating my symptoms. I have had days of ingesting alkaline water without any apparent increase in “symptoms/body aches.” However, I am beginning to question everything! Just curious…. do you drink alkaline water exclusively? Do you use filtered (R/O?) water in your Akai Water Ionizer?

            BTW… I am eager to consult with you but I am most certain that I am in need of the new lab work that is nearly available. At $475.00 plus a $195.00 consultation fee, and knowing I will need the same for my son as well, has me a bit shaken; but I know we need the information in order to be able to move forward with our health. Thanks for being the mad scientist who is willing to connect the dots to these fascinating and frustrating health issues.

          • Dr Ben January 27, 2012 at 1:19 am #

            Elizabeth –

            I want to be able to offer quantity discounts on the new test. I am talking with the lab about this. Let me work on them ;)

            I use my Akai Ionizer exclusively at home but I drink filtered water at my office using a standard 10 stage water filter.

            You react to so many supplements likely due to detoxing too quickly or having other mutations that cause various biochemical pathways to operate differently – not to mention that perhaps you are taking the wrong ones or too much.

          • Angela March 6, 2014 at 3:40 pm #

            My son is extremely sensitive to pretty much any changes in diet, supplements or water type it seems. Something I have learned the last year:
            a) Make any introduction or exit of a product (food or water) VERY SLOWLY – weeks not days – days not hours —
            b) ALWAYS MAKE ONE CHANGE ONLY AT ONCE. Otherwise you will NEVER know how you are reacting to it.

            People are inpatient – I am inpatient. I want to see my own or someone’s human suffering stop immediately. That is normal. But if you think of nature and watch the seasons; you can see how slowly and gradually nature changes her leaves from buds, her flowers from leaves. Right? Not to get too poetic, but we can learn from this. So the only way to know if it is alkaline water and not something else is to try and stay as close to the same diet, rest pattern, exercise pattern, and supplement pattern as before and then try it. On this though – I have read that those with mineral imbalances may react and it is wiser to take structured water (same as alkaline water am guessing) only once per week until minerals are more balanced (from loads of vegetable soups, etc.). Cheers, Angela

  2. Natalia February 12, 2012 at 7:07 am # Reply

    Hi Ben,
    Instead of the bioplasma cell salts in tablet form that contain lactose, can we use the homeopathic spray? If so, how many sprays? Thanks!

    • Dr Ben February 12, 2012 at 7:41 am # Reply

      Natalia –

      You may just skip the Bioplasma cell salts. Homeopathic sprays are different than cell salts and may cause issues.

  3. Betty March 15, 2012 at 7:09 pm # Reply

    Hi Dr. Ben,
    I have a few questions about the ade. First, my almost 3 month old has had bad colic and reflux. She was born via c-section at 37 weeks. She’s my 5th child. I have had adrenal/CFS issues my whole life and during this last pregnancy, it was discovered that I have 2 copies of C677T and FVL after developing a large clot.

    That’s my background! I’ve started your protocol of supplements and this drink. I have two questions about the drink. Can I mix up a 3-cup serving and just sip from it during the day? (I just gulped a whole 8oz of it just now–it was good!).

    Also, I have eliminated dairy, soy, and gluten (I have celiac anyways), to see if it will help the baby with her gas pains. I didn’t realize that the BioPlasma salts had lactose in them. Do you think it is enough to cause a problem in the baby?

    I’ve been off all gluten since before pregnancy and off of dairy and soy for a week. She is a bit happier during the day, but the nights are still awful. I’m not sure if the dairy was the culprit or not. I really miss my 24 hour cultured homemade yogurt!

    • Julia December 1, 2012 at 11:48 pm # Reply

      Hi Betty! Have you had your nursling checked for tongue or lip tie?? They are a midline defect. My daughter has ties and is going to get the revised with a laser in a few weeks. She has ‘reflux’ which is actually caused by her bad latch and her tongue not being able to properly cup the nipple while nursing. I know in my tongue tie group, many moms are finding out they have MTHFR mutations.. It certainly is worth a quick look in her mouth. Ties are actual birth defects that need to be taken care of by a highly skilled provider. Dr. Kotlow in Albany is the most knowledgeable and wonderful dentist. Check his sites for info and pics to help you diagnose any ties. Good luck mama!

  4. Diane April 16, 2012 at 8:35 am # Reply

    Hi ~ wondering if Concentrace by Trace Minerals Research could be used in the drink instead of the Elyte Electrolytes? Is there any reason it wouldn’t be good? Thanks!

  5. Tara July 2, 2012 at 9:02 pm # Reply

    Hi Dr. Ben,

    I’m following a low-oxalate protocol, and Vit. C sends me reeling, as it’s high ox. Is there an alternative to that ingredient, or any product you might recommend?


    • Dr Ben July 3, 2012 at 6:29 am # Reply

      Tara –

      Not sure off hand – have to think about it – happy to have anyone else jump on this for help! ;)

      I also am wondering why low oxalate has to be followed for some people.

      Oxalates are supposed to be readily processed by the gut and bacteria – so my guess – in order to begin eating oxalates once again is to heal your gut.

      • Tara July 3, 2012 at 6:33 am # Reply

        Thanks for your quick response!

        Oh yeah, my gut is a mess… (only eating three foods) Crohn’s since age 13, ileostomy at 23. But, you’ll find out more when I make my consult appointment and send you my info. ;) Hope you’re ready for a big challenge! (I’m C677TT, btw)

        • Angela March 6, 2014 at 4:06 pm # Reply

          We were recommended an “earth based” probiotic/prebiotic for our teenage son (who has been diagnosed with intestinal dysbiosis as well as “mood disorder”) and I think it helped. It was take for two weeks (2 pills) and then one week (1 pill) and then 2 pills a week maintenance for “leaky gut”. It’s called PRESCRIPT–ASSIST (distributed by LL Magnetic Clay Inc.) is available on amazon. It costs an arm and a leg, but if it helps I guess it is worth it.

          Also, as our son has CBS mutation (along with MTHFR, but not COMT) – so we need to be careful and address lowering ammonia and sulfate levels for 4-6 weeks, prior to methyl donors. Like my previous post – its like watching spring hit Seattle – its slow.. !
          Cheers, Angela

      • Lynn_M July 3, 2012 at 7:20 am # Reply

        I wonder if the type of Vitamin C would make a difference. The most available commercial form is ascorbic acid. Then there’s another form, sodium ascorbate, considered superior to ascorbic acid. And finally, lypo-spheric Vitamin C, which is sodium ascorbate delivered via “smart” lyposomal nanospheres. Since it is so bio-available, maybe it doesn’t have to get processed by the gut and bacteria and wouldn’t create oxalate problems.

        • Lynn_M July 3, 2012 at 7:27 am # Reply

          I should add that the lyposomal nano-sphere vitamin C, which comes in 5.7 ml packets of a colloidal gel, would be best consumed quickly by itself on an empty stomach and not used as a drink ingredient. But it’s supposed to dramatically increase the amount of supplement actually usable by the body.

          • Diane July 3, 2012 at 3:30 pm #


            Any more info on the lyposomal nano-sphere would be appreciated.

            I’ve had to take large amounts of vitamin C, 12 grams being the minimum maintenance dose. Even using the ascorbate form, I’m not comfortable with the idea it may be causing esophageal erosion or excess acidicism.


        • Tara July 3, 2012 at 4:16 pm # Reply

          Thanks, Lynn. Unfortunately, Vit C has adverse affects with regard to oxalates regardless of how it’s administered. I found that out while doing Vit C IVs…no fun.

          • Lynn_M July 3, 2012 at 6:52 pm #

            I suggest you go to the Vitamin C Foundation forum and ask your question there. I searched on oxalate at that forum and got 54 hits. If none of those answer your question, you could register and start your own thread.

        • Lynn_M July 3, 2012 at 6:41 pm # Reply


          Lypo-spheric Vitamin C is made by Livon Labs. If you go to their website http://www.livonlabs.com/, they have information about it and links to other sources. Dr. Tom Levy has written a book about Vitamin C, and I have heard interviews with him wherein he recommends the lypo-spheric form.

          At the Vitamin C Foundation Discussion Forum http://www.vitamincfoundation.org/forum/ there are a number of comments about lypo-spheric Vitamin C from users that take mega doses of Vitamin C.

          There are many other sites that sell lypo-spheric Vitamin C, and at a better price.

          • Lynn_M July 3, 2012 at 8:19 pm #

            This discussion is pertinent to your issue: http://www.vitamincfoundation.org/forum/viewtopic.php?f=3&t=7701&hilit=vitamin+c+causes+oxalate+reaction

          • Dr Ben July 3, 2012 at 10:44 pm #

            Diane and Lynn –

            I’ve provided the Lypo-Spheric Vitamin C for quite a few years and I’ve now ended up developing my own for various reasons.

            Optimal Liposomal Vitamin C is different than Lypo-Spheric Vitamin C in a few ways:
            – uses non-hydrogenated phosphatidylcholine
            – ‘more slippery’
            – consistent liposomal size and shapes
            – less packaging
            – easier to take
            – better taste

          • Lynn_M July 3, 2012 at 11:46 pm #

            Dr. Ben,
            Good to know about the features of your Optimal LIposomal Vitamin C.

    • Lynn D July 16, 2013 at 3:12 am # Reply

      I tried D Ribose several yrs ago and it made me more tired (I used a forth of amount they said to on label) tried a few times with same reaction.

    • Lynn D July 16, 2013 at 3:14 am # Reply

      Tara, maybe try lemon or other vite C fruit or veg jc. hope wont be too acidic for teeth though.

  6. Julie Cuthbert August 1, 2012 at 3:02 pm # Reply

    Is this drink safe while pregnant?

    • Dr Ben August 1, 2012 at 5:55 pm # Reply

      Hi Julie –

      It all depends on the individual and their symptoms/conditions.

      Electrolytes and vitamin C are quite safe in general. Electrolytes may increase blood pressure due to the sodium content. Definitely monitor your blood pressure during pregnancy –

      I am not sure about D-Ribose. I have not seen anything negative about D-Ribose and pregnancy – but I have not seen anything positive either. You’ll have to ask your OB/GYN and/or midwife.

      The cell salts are totally fine during pregnancy.

  7. Dolores Seames October 6, 2012 at 4:41 pm # Reply

    Dr. Ben,
    Can the MTHFRade cause a detox reaction? Or maybe could I be reacting to the Bioplasma cell salts? I only tried half of the liter dring yesterday, and last night throught this morning, I had stomach and intestinal discomfort and pain with lots of gas. This morning, I’ve been expelling gas and mucas with my bowel movements. I am dairy free, as I know it bothers me, but have no idea if it has anything to do with lactose. I have also been on the GAPS diet for a little over a year, but have used a few other homeopathic medications with lactose. My doctor said that using them under my tongue would not cause problems because the lactose wouldn’t reach my intestines.

    Please advise. If I continue, will the digestive issues improve? I am have 2 copies of T667C mutation, severe adrenal fatigue, and take thyroid medication, TADS, and just started Isocort. I get extremely fatigued, get dry eyes, and get occasional heart palpitations, which has improved since starting the TADS.

    • MaryS October 7, 2012 at 10:33 pm # Reply

      Hi Dolores, I had a little gas when i first started drinking this (minus the cell salts) so I started diluting it. Now I can drink it straight with no problems. Not sure why i had to build up. I also wanted to pass along that Dr Ben told me to get the electrolytes from allergy research group at health goods instead of the one from seeking health because of my CBS mutation. So, anyone trying to minimize sulfur may one to get that one.

      Also wondering if the cell salts are OK for those of us with CBS? I notice some of the salts have the word sulfate in the name.

      • Dolores Seames October 7, 2012 at 11:01 pm # Reply

        Thanks Mary, Wow, I didn’t realize that the E lyte has sulfate in it. I did get it from Health E Goods. I was also wondering about the cell salts, especially since they are such low potency, as they would have more of the actual minerals in it.
        Now I’m wondering if I should be using the e lyte. I just checked and there is another liquid concentrate, but it is a couple more dollars. I guess I thought I should use the one Dr. Ben recommended here in his formula. I wish I had known before buying it and using it. Today, I have a headache, and dryer eyes. I also got nausous after drinking a little this morning, so don’t know why that would be? The gas is less today. I only go through about 1/2 of it in the day, and I mix it with coconut water so it tastes better, and dilutes it a bit more. The first time, I only used 1/2 of the D-Ribrose, since I’m cautious about starting something new. Today I used the 1 scoop, or t.. I wonder if that could cause the nausea and or headache?
        I did sleep for 6 1/2 straight hours last night for the first time in many years. I don’t know if it is this drink helping, or the Isocort I started. I also took a capsule of Seraphos last night, so might have been that.

  8. Natalie December 16, 2012 at 5:18 am # Reply

    Hi Dr. lynch,
    You said the mthfr drink is supposed to help decrease urination. Is this caused by low adrenals or aomehing else? I have low adrenals and very frequent urination. I am also homozygous mthfr677tt.
    Please explain.

    • Dr Ben December 20, 2012 at 6:03 am # Reply

      Natalie –

      Frequent urination may be caused by decreased output of aldosterone.

      Aldosterone is produced by the adrenals. When fatigued, the adrenals do not produce as much aldosterone and frequent urination occurs.

      When your adrenals are optimal, the frequency of urination should normalize – if the frequent urination is due to adrenal insufficiency.

  9. Marie December 18, 2012 at 8:56 pm # Reply

    Wow. That’s funny. I have mixing putting C, magnesium, Concetrace and Ribose into water before I work out, and it works great. That sounds very similar to what you’re suggesting. Good to her I’m on the right track!

  10. Dolores Seames January 4, 2013 at 2:44 pm # Reply

    Dr. Ben,
    I thought homeopathics had to be used under the tongue, 15 minutes before eating or drinking anything, to be effective. So why do you put it into the drink? Also, 30 tablets seems like a lot in one day. Can that many be used if placed under the tongue at intervals through out the day? My doctor has said that lactose is not a problem when placed under the tongue, because it dissolves into the tissues, and doesn’t get to the intestines.
    I’ve heard some great things about the bioplasma cell salts, but none that have added it to a drink.
    Please advise.

    • Dr Ben January 4, 2013 at 5:37 pm # Reply

      Dolores –

      These are cell salts – not homeopathics. They function differently.

      Yes – you are right that one should not mix homeopathics with anything nor would they use 30 tablets.

      Cell salts are not energetic like homeopathics as they are not percussed.

      • Dolores Seames January 4, 2013 at 5:49 pm # Reply

        Thank you for the explanation. That helps. Would it be better for those who may have an issue with lactose to use them sublingually instead of in the drink?

        • Dr Ben January 4, 2013 at 6:22 pm # Reply

          The amount of lactose in the cell salts is pretty minimal. However, if you are sensitive, then I’d consider using probiotics that helps digest lactose. Consider taking 1 capsule of ProBiota 12 after dinner each evening. You may find your lactose intolerance reduces over time. You may like to know that you can make your own lactose free milk, yogurt, cream, etc using Lactase Drops.

          Keep in mind that you are also diluting the amount of lactose in a full liter of water thereby reducing the effective lactose concentration.

          Sublingually may help – you’d have to try and see how you respond.

  11. Michelle March 8, 2013 at 9:06 am # Reply

    I can’t wait to try this. Professional Formulas has a liquid (no lactose) Cell Salt Combination. It is the same formula as the BioPlasma.

    Is the d Ribose GAPS legal?

    Thanks for all the great info.

  12. Elisa August 18, 2013 at 1:49 pm # Reply

    I am compound heterozygous and 5 months pregnant. I’ve been taking the Active B12 + L-5-MTHF since week 4 of pregnancy. I recently purchased the protocol for pregnant women. I also purchased the ingredients for MTHFRade. I just want to make sure that it is safe to take the MTHFRade while pregnant. I would assume so, but one can never be too cautious.

  13. sul September 25, 2013 at 8:52 pm # Reply

    hi Dr Ben

    have you changed your recipe of the MTHFRade?
    I dont see the bioplasma salts anymore in it?

    • Dr Lynch September 25, 2013 at 10:45 pm # Reply

      Hi Sul – you may add bioplasma – that works well. I simplified it a bit – but yes – still may add that and likely a good idea.

      Also consider adding creatine – as creatine is such a sink for SAMe. About 60-70% of SAMe is used to make creatine on a daily basis. Next item that is hot on the list for SAMe usage is phosphatidylcholine. Combined, these two make up the bulk of SAMe utilization each day.

  14. sul October 9, 2013 at 1:08 am # Reply

    Hi Dr Ben
    I could not find the quantity of bioplasma salts to be used in the mthfrade.
    How many tablets in one liter of water?

    I have bought all the ingredients from seekinghealth. There is no scoop in the vitamin C jar. I believe one scoop equals one teaspoon. Am I right?

    Thank yoh

    • Dr Lynch October 9, 2013 at 4:46 am # Reply

      Hello –

      Simply add about 30 tablets or so of Bioplasma – per liter.

      One serving = one teaspoon. You may increase or decrease any of the ingredients as you like.

      Dr Lynch

  15. Ina O'Con nor November 8, 2013 at 3:28 pm # Reply

    Have you had experience with MTHFRade in children?

  16. Marci January 23, 2014 at 9:58 pm # Reply

    Dr. Lynch,
    I am interested in purchasing the ingredients for MTHFRade on seekinghealth. I have two questions about the recipe. I know that we are supposed to do C+electrolytes+K but I am not seeing the vitamin K in the recipe. Is this something I should add and how much/what form do you recommend? I would also like to know about the importance of creatine as an ingredient. What are it’s benefits/can I leave it out? Thanks for your time, Marci

  17. Heather Brandt March 10, 2014 at 4:14 pm # Reply

    Is it possible to make this without vitamin c powder b/c my mother and I have hemochromatosis (on top of MTHFR ) and are supposed to not use vitamin C supplements due to it causing us to absorb even more iron (due to the hemochromatosis)?

    • Dr Lynch March 11, 2014 at 3:38 am # Reply

      absolutely – just a basic recommendation. Adjust as you and your doc see fit.

  18. Diana March 15, 2014 at 11:03 pm # Reply

    Would it ruin the effects of this mixture to heat it up, like a tang-tea? I sip tea all day long because I’m always cold, so I am imagining that would be easier for me once I start using this formula, if it’s possible.


    • Dr Lynch March 16, 2014 at 4:19 am # Reply

      hi Diana – not sure. Don’t boil it for sure – but having it warm is likely just fine.

  19. Linda April 6, 2014 at 6:45 pm # Reply

    Hi Dr. Ben … I just found out I have MTHFR mutation C677T and going thru your site to educate myself. Found your recommendation and recipe for MTHFRade. Was going to order all ingredients and then discovered the Optimal Creatine is no longer available and no dates as to IF or when it will be available. I was excited to hear about your formula and now I’m really let down because all the ingredients are not available. Can you tell us if and when the Optimal Creatine will be available again?


    • Dr Lynch April 7, 2014 at 8:24 pm # Reply

      Hi Linda –

      Yes – Optimal Creatine will be available in less than 30 days or so. Sorry about running out. We’ve a lot on the way.

      We also have a new electrolyte blend coming in which I’m very excited about – will have creatine and some ribose and vitamin C already in it. This will be available in a few months time.

  20. drteray May 6, 2014 at 8:20 pm # Reply

    Hi Dr. Ben,
    Are you concerned about d-ribose lowering blood sugar? I always recommend that my patient take it with food for that reason.
    Have you had any problems with people taking it on an empty stomach?
    Thank you!

    • Dr Lynch May 7, 2014 at 7:19 pm # Reply

      Hi Teray –

      Only issue I’ve noticed with D-Ribose on an empty stomach is it may cause loose stools if too much is taken in.

      I have not experienced low blood sugar in people with it. You have any?

      • Diana May 7, 2014 at 10:21 pm # Reply

        Will the electrolyte blend be similar enough that it will potentially be a good replacement for mixing this on our own?

      • drteray May 8, 2014 at 12:44 am # Reply

        Only in myself – I drank a combination of ribose and l-carnitine on an empty stomach once and felt that classically “low blood sugar” feeling (lightheadedness mostly). The same did not occur when I took it with food.
        I don’t know if it was because of the drink itself, or just that I was already hungry, but I’ve always taken it with food or a smoothie ever since. The light-headedness effect has been noted by Dr. Steven Sinatra as well, albeit in doses higher than 10g.
        It’s good to know that this is not typical in your population. I may experiment on myself again and see what happens.
        Thank you!

        • Dr Lynch May 8, 2014 at 7:15 pm # Reply

          Try D-Ribose without the L-carnitine. The carnitine may have contributed to the light headedness.

          • drteray May 8, 2014 at 9:06 pm #

            I will try that. Thanks.

          • Lynn D May 30, 2014 at 1:44 pm #

            In the past had tried D-Ribose and , became to tired with an hour, had to take a nap (hadnt ck BP or BS which tend towards low till lately). Happened several times , so figured ribose is not for me or needed a conutrient with it.
            In way past had tried ALcarnitine and also became weaker feeling, did research and found effects some thyroids. (677TT). Am just trying for more energy and brain power. Is L-carnitine different then ALcarnitine?

  21. Joel Costello May 11, 2014 at 1:35 am # Reply

    Hi Dr. Lynch

    When will you be releasing an all-in-one mixture of this drink? Will it be available in Australia?

    I have homozygous A1298C and also have an overgrowth of E Coli and an undergrowth of Bifidobacterium and Lactobacillus! I have suffered from dizziness and a weird neurological swimmy feeling daily for two years, it is not vertigo and it gets worse after eating any carbohydrate! I am basically eating organic chicken breast for breakfast lunch and dinner!

    Does this indicate anything in particular to you, or should I just continue on with my methylguard plus, and continue with gut repair?

  22. Jess May 27, 2014 at 6:37 pm # Reply

    I am 39 weeks pregnant, but will be breastfeeding when they are born, and for as long as they want.

    Is the creatine and/or d-ribose safe to take while pregnant or lactating?

    • Dr Lynch May 28, 2014 at 4:04 am # Reply

      Hi Jess –

      Those nutrients are ok to take while nursing – but keep an eye on your baby’s symptoms – gas and diarrhea. D-Ribose can also cause some lightheadedness due to low blood sugar-like symptoms so be sure to take it after eating or close to a meal.

  23. David Mongeon June 13, 2014 at 6:45 pm # Reply

    I’m wondering if it is ok to make up a large quantity and refrigerate it. How long will it last in the fridge?

  24. Karen September 1, 2014 at 2:27 pm # Reply

    How important are the quercetin, hespendin, rutin? Can’t use Seeking Health C because of the corn since my doc, Dr. Osborne says no grain.

  25. Mara September 12, 2014 at 6:59 pm # Reply

    Hi Dr Ben,

    In other articles you mentioned taking Vitamin C at least 30 minutes apart from Folate. How would taking vitamin C throughout the day impact the folate? As long as it’s “timed release” (not all at once), it’s okay?

  26. veronica December 29, 2014 at 9:12 pm # Reply

    can I take more than one scoop per day say, one in the AM and one in the evening?

    • Dr Lynch December 29, 2014 at 9:46 pm # Reply

      Veronica – absolutely. I do – I take as needed and on some days I don’t take any. Just depends on how you feel and also the degree in which you feel fatigued or sweating.

      • veronica December 29, 2014 at 10:21 pm # Reply

        thank you, I was curious because a full scoop helped today and I feel the need for a bit more tonight. thank you again :)

  27. veronica December 30, 2014 at 2:33 am # Reply

    how much per day would be ok to give a 7 year old child?

  28. Kna January 30, 2015 at 9:34 pm # Reply

    Hi..is this drink diabetic (type2) friendly? Thanks.

    • Dr Lynch January 31, 2015 at 5:08 pm # Reply


      Note that it may support your blood sugar levels – keep an eye on that.

      I also HIGHLY recommend using liposomal vitamin C in addition to the electrolytes for type 2 diabetes. This combination really helps blood sugar stabilization. Also a solid multivitamin is recommended as there is lots of nutrient use and oxidative stress in type 2 diabetes.

      • Kna January 31, 2015 at 9:58 pm # Reply

        Thank you so much for the advice Dr Lynch.

      • Meg February 27, 2015 at 8:01 pm # Reply

        Hi Dr Lynch,
        I have been using this w/out B9 as a supplement, no matter which I use I feel terrible, but with the electrolyte drink it has helped! My question is, on my nutreval, I show high Taurine levels and PHE, is this okay to take? I feel better on it but wanted to make sure.
        I DO have QDPR and SLC22A1 as well, so I cannot tolerate lecithins well or liposomal C :(

        • Dr Lynch March 1, 2015 at 7:30 am # Reply

          Hi Meg –

          Yes – this is not much taurine in the electrolyte.

          Also – is the high taurine in the blood or is in the urine? or both?

          Taurine in blood is reflective on protein intake. If high, eating a lot of protein.

          In urine, taurine is also reflective of protein intake – but if low in the blood and high in the urine, it is reflective – typically – of yeast overgrowth or pathogen in the gut.

  29. Victoria February 25, 2015 at 11:19 pm # Reply

    I’m compound heterozygous with fibromyalgia and had been having side effects (I assume from the methylfolate) of fatigue and severe pain. I also have symptoms such as chronic dry mouth and eyes, feeling the need to urinate as soon as I drink water. So I tried Optimal Electrolytes for the first time today – a little less than one scoop in a glass of water that I drank over several hours. I had no bowel issues prior to drinking this, but now I’m having really bad diarrhea. No gas, no stomach cramps, just sudden diarrhea. Any idea what’s going on?

    • Dr Lynch March 1, 2015 at 7:40 am # Reply

      Hi Victoria –

      Sorry to hear about this.

      My thought would be that your ability to absorb nutrients is compromised.

      Evaluate your digestion with a comprehensive digestive and stool analysis by Doctors Data or a Nutreval by Genova. Have your docs order.

      You can also next time eat a meal – then drink the electrolytes.

      However, I do think your digestion is compromised and may need some healing.

      Please stop it for now until you get your digestion sorted out.

  30. Patricia March 14, 2015 at 4:34 pm # Reply

    Are there any SNPs or health issues where this drink would be contraindicated?

  31. Annette April 6, 2015 at 1:46 pm # Reply

    when I clicked on the link for the Electrolyte Concentrate one of the comments for this product is that is has sodium benzoate. In your information it indicates these are preservative free. Am I looking at the wrong product?

  32. Jenny April 9, 2015 at 5:55 am # Reply

    I’m allergic to citrus. Any alternative to the Optimal Vitamin C Powder? Thanks. The


  1. MTHFRade | Loving Our Guts - February 29, 2012

    […] Ben Lynch posted this post about a drink he invented MTHFRade a week or two […]

  2. Leptin Reset Update #2 | Loving Our Guts - March 1, 2012

    […] already am noticing an improvement. I have now ordered all of the ingredients for Dr Ben’s MTHFRade from Amazon and expect them later this week. I’m skipping the vitamin C because the body […]

  3. Leptin Reset Update #2 | Loving Our Guts - March 2, 2012

    […] Bioplasma and already am noticing an improvement. I have now ordered all of the ingredients for Dr Ben’s MTHFRade from Amazon and expect them later this week. I’m skipping the vitamin C because the body […]

  4. MTHFR Mutation- C677T | Lyme Disease Mommy - May 20, 2012

    […] Drink at least two liters of filtered water daily mixed with vitamin C and electrolytes. […]

  5. How to Manage MTFHR Mutations for Optimum Fertility and a Healthy Pregnancy | Natural Fertility Breakthrough - November 28, 2012

    […] Drink at least two liters of filtered water daily mixed with vitamin C and electrolytes. […]

  6. The Fibromyalgia Chronic Fatigue MTHFR Gene Mutation Link | The Health Chocoholic - January 9, 2014

    […] Dr. Ben Lynch “MTHFRade is the MTHFR Drink Formula.  Have Yours Yet?” http://mthfr.net/mthfrade-is-the-mthfr-drink-formula-have-yours-yet/2012/01/19/ […]

  7. Supplement Savvy Sunday #2: Dr. Lynch’s MTHFR C677T Mutation Protocol | Diary of a Mutant 30-Something: Living with MTHFR - August 17, 2014

    […] “MTHFRade” is the MTHFR Drink Formula. Have yours yet? […]

  8. More About MTHFR | Infertility: A Lifestyle Blog - August 25, 2014

    […] Drink at least two liters of filtered water daily mixed with vitamin C and electrolytes. […]

  9. MTHFR Basics – stewarding Life - February 19, 2015

    […] Drink at least two liters of filtered water daily mixed with vitamin C and electrolytes. […]

Leave a Reply

Read previous post:
Methylfolate: Taking too much a problem?

I recently received an excellent pair of questions from a client of mine and wanted to share the dialogue with...