Recurrent miscarriage can be associated with MTHFR.
Does this sound familiar?
“I was just told by my high risk OB that there is no research proving MTHFR is connected to miscarriage.”
If it does, your OB is not educated correctly about MTHFR.
Let me show you something which will disprove the naysayers immediately.
This image below comes straight from the CDC (Centers for Disease Control AND Prevention)
source: CDC Phenopedia
The #1 gene associated with recurrent miscarriage is Factor V Leiden (F5).
This is known and accepted in medicine.
What is the #2 most researched gene associated with recurrent miscarriage?
MTHFR with 74 research papers and 5 meta analyses.
There is conflicting evidence. Yes. Some papers say MTHFR is associated with recurrent miscarriage and others say it is not.
“Several case-control studies were investigated MTHFR C677T polymorphism as risk for recurrent pregnancy loss (RPL). These studies rendered contradictory results, some indicating that the polymorphism is associated with the risk of RPL whereas others concluded there is no association.”
Why are their contradictory results?
Because some women with MTHFR polymorphisms consume leafy green vegetables, limit folic acid intake and have their methylation cycle working well.
Some women with MTHFR polymorphisms have a different story and life experience and their methylation cycle is not working well.
Just because you have a MTHFR polymorphism does not automatically say you are going to have recurrent miscarriages.
What having the MTHFR polymorphism does say is you have an increased risk for recurrent miscarriages.
For years, since 2011, I have been teaching and educating many people around the world about MTHFR.
How many times do you think I’ve heard this?
“Just had my OB tell me MTHFR is a variant akin to having eye color and everyone’s eye color is different and there is no need to do any kind of treatment . Big eye roll. I lost 6 pregnancies and since taking methylated B’s I’ve had 3 back to back pregnancies.”
I’ve heard it a ton.
- If you are having recurrent miscarriage, you seriously need to consider doing genetic testing with your doctor. Check for F5 and MTHFR for starters.
- If you have ordered genetic testing from 23andMe or Genos Research, you can use StrateGene to point out key polymorphisms such as MTHFR and F5
- Remove folic acid and start using more active forms of nutrients which your body – and your baby – can efficiently use.
- Learn. The. Science. A great informational video is here on ‘Folic acid and Pregnancy’ – along with over 353 brilliant comments posted by readers.